Shared and independent roles of CGRP and PACAP in migraine pathophysiology
Abstract The neuropeptides calcitonin gene-related peptide (CGRP) and pituitary adenylate cyclase-activating polypeptide (PACAP) have emerged as mediators of migraine pathogenesis.Both are vasodilatory peptides that can cause migraine-like attacks cho-pat strap elbow when infused into people and migraine-like symptoms when injected into rodents.In